Objective: To assess the effectiveness of exercise therapy added to general practitioner (GP) care compared with GP care alone, in patients with hip osteoarthritis (OA) during 12 months follow-up. Methods: We performed a multi-center parallel pragmatic randomized controlled trial in 120 general practices in the Netherlands. 203 patients, aged ≥45 years, with a new episode of hip complaints, complying with the ACR criteria for hip OA were randomized to the intervention group (n = 101; GP care with additional exercise therapy) or the control group (n = 102; GP care only). GP care was given by patient's own GP. The intervention group received, in addition, a maximum of 12 exercise therapy sessions in the first 3 months and hereafter three booster sessions. Blinding was not possible. Primary outcomes were hip pain and hip-related function measured with the HOOS questionnaire (score 0-100). Results: The overall estimates on hip pain and function during the 12-month follow-up showed no between-group difference (intention-to-treat). At 3-months follow-up there was a statistically significant between-group difference for HOOS pain -3.7 (95% CI: -7.3; -0.2), effect size -0.23 and HOOS function -5.3 (95% CI: -8.9; -1.6), effect size -0.31. No adverse events were reported. Conclusions: No differences were found during 12-months follow-up on pain and function. At 3-months follow-up, pain and function scores differed in favor of patients allocated to the additional exercise therapy compared with GP care alone. Trial registration: The Netherlands Trial Registry NTR1462.

Disability, Exercise therapy, Hip osteoarthritis, HOOS, Pain, Physiotherapy
dx.doi.org/10.1016/j.joca.2015.07.023, hdl.handle.net/1765/84786
Osteoarthritis and Cartilage
Department of Orthopaedics

Teirlinck, C.H, Luijsterburg, P.A.J, Dekker, J, Bohnen, A.M, Verhaar, J.A.N, Koopmanschap, M.A, … Bierma-Zeinstra, S.M. (2016). Effectiveness of exercise therapy added to general practitioner care in patients with hip osteoarthritis: A pragmatic randomized controlled trial. Osteoarthritis and Cartilage, 24(1), 82–90. doi:10.1016/j.joca.2015.07.023