Objectives Little is known about local access-site complications and upper extremity dysfunction after transradial percutaneous coronary procedures (TR-PCP). This systematic review study aimed to summarise the current knowledge on the incidences of access-site complications and upper extremity dysfunction after TR-PCP. Methods Two independent, trained investigators searched MEDLINE, EMBASE and CENTRAL for eligible studies published before 1 January 2015. Also, they hand-searched the conference proceedings of the annual scientific sessions of the American College of Cardiology, the American Heart Association, European Society of Cardiology, and the Trans-catheter Cardiovascular Therapeutics. Inclusion criteria were cohort studies and clinical trials discussing the incidence of access-site complications and upper extremity function after transradial percutaneous coronary intervention (TR-PCI) and/or transradial coronary angiography (TR-CAG) as endpoints. Results 176 articles described access-site complications. The incidence is up to 9.6 %. Fourteen articles described upper extremity dysfunction, with an incidence of up to 1.7 %. Upper extremity dysfunction was rarely investigated, hardly ever as primary endpoint, and if investigated not thoroughly enough. Conclusion Upper extremity dysfunction in TR-PCP has never been properly investigated and is therefore underestimated. Further studies are needed to investigate the magnitude, prevention and best treatment of upper extremity dysfunction. Optimising TR-PCP might be achieved by using slender techniques, detection of upper extremity dysfunction and early referral to a hand rehabilitation centre.

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doi.org/10.1007/s12471-015-0747-9, hdl.handle.net/1765/84835
Netherlands Heart Journal
Department of Cardiology

Zwaan, E. M., Koopman, A. G. M. M., Holtzer, C. A. J., Zijlstra, F., Ritt, M. J. P. F., Amoroso, G., Moerman, E., Kofflard, M.& IJsselmuiden, A. (2015). Revealing the impact of local access-site complications and upper extremity dysfunction post transradial percutaneous coronary procedures. In Netherlands Heart Journal (Vol. 23, Number 11, pp. 514–524).https://doi.org/10.1007/s12471-015-0747-9