Etiologic and diagnostic facets of Creutzfeldt-Jakob disease: The effect of genes and environment
Etiologische en diagnostische aspecten van de ziekte van Creutzfeldt-Jakob: invloed van genen en omgeving
Transmissible spongiform encephalopathies (TSE) or prion diseases constitute a fascinating group of neurological disorders. In spite of their rarity, their unique etiopathological mechanisms and epidemiological aspects have attracted a considerable number of researchers. This thesis focuses on two facets: etiological mechanisms and diagnostic tests of Creutzfeldt-Jakob disease (CJD). We have searched new insights into these two topics using genetic and classic epidemiological methodology. For the studies presented in this book, we have used data from the Dutch, Italian and UK CJD National Surveillance Systems, the 'European collaborative Study group of CJD' (EUROCJD), the 'extended European collaborative Study group of CJD' (NEUROCJD), the 'Early clinical diagnosis of human spongiform encephalopathies by analysis of biological fluids-CJD Markers collaboration' (EPICJD), and the 'Rotterdam Study'.
|R.G. Will (Robert)|
|Erasmus University Rotterdam|
|Duijn, Prof. Dr. C.M. van (promotor), Will, Prof. Dr. R.G. (promotor)|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
Sánchez-Juan, P.J. (2007, January 24). Etiologic and diagnostic facets of Creutzfeldt-Jakob disease: The effect of genes and environment. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/8484