On 5-7 May 2014, the World Health Organization (WHO) convened the second integrated meeting on"influenza vaccines that induce broadly protective and long-lasting immune responses". Around 100invited experts from academia, the vaccine industry, research and development funders, and regulatoryand public health agencies attended the meeting. Areas covered included mechanisms of protection innatural influenza-virus infection and vaccine-induced immunity, new approaches to influenza-vaccinedesign and production, and novel routes of vaccine administration. A timely focus was on how thisknowledge could be applied to both seasonal influenza and emerging viruses with pandemic potentialsuch as influenza A (H7N9), currently circulating in China. Special attention was given to the developmentof possible universal influenza vaccines, given that the Global Vaccine Action Plan calls for at least onelicensed universal influenza vaccine by 2020. This report highlights some of the topics discussed andprovides an update on studies published since the report of the previous meeting.

doi.org/10.1016/j.vaccine.2015.10.014, hdl.handle.net/1765/85072
Department of Virology

Cox, N., Hickling, J., Jones, R., Rimmelzwaan, G., Lambert, L. C., Boslego, J., … Ortiz, J. R. (2015). Report on the second WHO integrated meeting on development and clinical trials of influenza vaccines that induce broadly protective and long-lasting immune responses: Geneva, Switzerland, 5-7 May 2014. In Vaccine (Vol. 33, pp. 6503–6510). doi:10.1016/j.vaccine.2015.10.014