A 77 year old man presents with a progressive purple lesion on the dorsal aspect of the left upper leg and an unexplained high ESR and CRP. A "particle disease" bursitis caused by polyethylene wear of his left hip prosthesis, was diagnosed. Particle disease is a granulomatous inflammation resulting from macrophage reaction to any of the components of the arthroplasty surface. It is a complication of (polyethylene)prosthesis that is relentlessly progressive with loosening, fracture and destruction of bone.

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Nederlands Tijdschrift voor Dermatologie en Venereologie
Erasmus MC: University Medical Center Rotterdam

Siemerink, M., Verhaegh, M., & Krekels, G. (2012). A surprising diagnosis for the dermatologist. Nederlands Tijdschrift voor Dermatologie en Venereologie, 22(9), 568–569. Retrieved from http://hdl.handle.net/1765/85128