The current 7-year follow-up study investigated: (1) the stability of ASD severity, and (2) associations of ASD severity in adolescence with (a) childhood and concurrent psychiatric comorbidity, and (b) concurrent societal functioning. The Autism Diagnostic Observation Schedule (ADOS) and the Diagnostic Interview Schedule for Children were administered in childhood (ages 6–12) and in adolescence (ages 12–20) to 72 individuals with a pervasive developmental disorder-not otherwise specified (PDD-NOS). ADOS calibrated severity scores showed a large stability (r = .51). Psychiatric comorbidity in childhood and adolescence were not associated with ASD severity in adolescence. Mental health care use (87 %) and special education needs were high (71 %). Reevaluation of ASD severity and psychiatric comorbidity later in life seem useful when PDD-NOS is diagnosed in childhood.

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Keywords Autism Diagnostic Observation Schedule (ADOS-2), Autism spectrum disorders (ASD), Comorbid psychiatric disorders, Follow-up, Pervasive developmental disorder-not otherwise specified (PDD-NOS), Societal functioning, Symptom severity
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Journal Journal of Autism and Developmental Disorders
Louwerse, I, Eussen, M.L.J.M, van der Ende, J, de Nijs, P.F.A, van Gool, A.R, Dekker, L.P, … Greaves-Lord, K. (2015). ASD Symptom Severity in Adolescence of Individuals Diagnosed with PDD-NOS in Childhood: Stability and the Relation with Psychiatric Comorbidity and Societal Participation. Journal of Autism and Developmental Disorders, 45(12), 3908–3918. doi:10.1007/s10803-015-2595-2