Objectives. Stenting for native and recurrent Coarctation (COA) in adults has become an important therapeutic strategy. In this prospective observational study we evaluated the intermediate- term outcome of stent implantation for either native or recurrent (re)COA in adults. Methods. All adults who underwent stent implantation in our institution between January 2003 and December 2008 were included. Diagnosis of (re)COA was based upon a combination of clinical signs, noninvasive imaging or invasive gradient measurements. NuMED stents were implanted under general anaesthesia. Results. Twenty-four patients (50% male) underwent stent implantation for native (n=6) or reCOA (n=18) at a median age of 36 (18 to 60) years. There was significant improvement in pre- versus post-stent invasive systolic gradient (19 vs. 0 mmHg, p<0.001) and COA Diameter (10 vs. 16 mm, p<0.001). Acute complications (12.5%) included death due to aortic rupture despite immediate successful coverage with a covered stent (n=1) and groin haematoma (n=2). During a median follow-up period of 33 (8 to 77) months (n=22), late complications occurred in three patients (13.6%): stent migration to the ascending aorta (n=1), pseudoaneurysm at the site of the initial stent (n=1), and occluded external iliac artery (n=1). Stent implantation did not reduce the need for antihypertensive medication or blood pressure at last follow-up. Conclusion. COA stenting results in a significant gradient decrease and increase in vessel diameter. However, serious complications do occur and hypertension remains in the majority of patients.

Aortic coarctation, Catheter intervention, Congenital heart disease
hdl.handle.net/1765/85596
Netherlands Heart Journal
Department of Internal Medicine

Moltzer, E, Roos-Hesselink, J.W, Yap, S.C, Cuypers, J.A.A.E, Bogers, A.J.J.C, de Jaegere, P.P.T, & Witsenburg, M. (2010). Endovascular stenting for aortic (re)coarctation in adults. Netherlands Heart Journal, 18(9), 430–436. Retrieved from http://hdl.handle.net/1765/85596