A fox circovirus was identified in serum samples from foxes with unexplained neurologic signs by using viral metagenomics. Fox circovirus nucleic acid was localized in histological lesions of the cerebrum by in situ hybridization. Viruses from the family Circoviridae may have neurologic tropism more commonly than previously anticipated.

dx.doi.org/10.3201/eid2107.150228, hdl.handle.net/1765/85745
Emerging Infectious Diseases - (Open Access)
This work was funded by the European Commission 7th Framework Programme; grant id h2020/643476 - COllaborative Management Platform for detection and Analyses of (Re-)emerging and foodborne outbreaks in Europe (COMPARE)
Erasmus MC: University Medical Center Rotterdam

Bexton, S, Wiersma, L.C.M, Getu, S, van Run, P.R.W.A, Verjans, G.M.G.M, Schipper, D, … Smits, S.L. (2015). Detection of circovirus in Foxes with Meningoencephalitis, United Kingdom, 2009–2013. Emerging Infectious Diseases - (Open Access), 21(7), 1205–1208. doi:10.3201/eid2107.150228