Although influenza A/H1N1pdm09 is not causing a pandemic anymore, we recently observed two critically ill pregnant women infected by this virus. We present these cases to illustrate the possible severe complications of an - at that moment - seasonal influenza in pregnancy. We discuss the epidemiological differences between the pandemic and post pandemic phase and try to explain the high virulence of influenza A/H1N1pdm09 -infections in pregnancy by discussing insights in immunology during pregnancy. We conclude that although influenza A/H1N1pdm09 is in the post pandemic phase, infection by this influenza virus still needs to be considered in pregnant women with progressive respiratory dysfunction.

dx.doi.org/10.4084/mjhid.2015.007, hdl.handle.net/1765/86161
Mediterranean Journal of Hematology and Infectious Diseases
Department of Gynaecology & Obstetrics

Bogers, H, Bos, D, Schoenmakers, S, & Duvekot, J.J. (2015). Postpandemic influenza A/H1N1pdm09 is still causing severe perinatal complications. Mediterranean Journal of Hematology and Infectious Diseases, 7(1). doi:10.4084/mjhid.2015.007