Bisphosphonates may cause extensive osteonecrosis of the mandible or maxilla. This rare, but serious and difficult-to-treat complication is known as BRONJ (bisphosphonate-related osteonecrosis of the jaw). If one is not familiar with its clinical presentation, the condition could be confused with a malignant tumor, resulting in unnecessary additional diagnostics. In this article, a patient with BRONJ is discussed and an overview of the literature is given.
Het Nederlands Tijdschrift voor Keel- Neus- Oorheelkunde
Erasmus MC: University Medical Center Rotterdam

Bernard, S.E, Mast-Kramer, H, & Datema, F.R. (2015). Bisphosphonate-related osteonecrosis of the jaw. Het Nederlands Tijdschrift voor Keel- Neus- Oorheelkunde, 21(4), 186–189. Retrieved from