Individual risk stratification of gastric cancer: Evolving concepts and their impact on clinical practice
Best Practice and Research in Clinical Gastroenterology , Volume 28 - Issue 6 p. 1043- 1053
Gastric cancer (GC) is the third leading cause of cancer-related death worldwide and it mostly develops in long-standing inflammatory conditions, and Helicobacter pylori-gastritis, in particular. Despite the increasing understanding of both the phenotypic alterations and the molecular mechanisms occurring during GC multi-step carcinogenesis, no reliable biomarker is available to be reliably implemented into GC secondary prevention strategies. Multidisciplinary diagnostic approaches integrating endoscopy, serology, histology and molecular profiling currently appears as the most appropriate approach for patients' stratification into different GC risk classes.
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|Best Practice and Research in Clinical Gastroenterology|
|Organisation||Department of Gastroenterology & Hepatology|
Rugge, M, Capelle, L.G, & Fassan, M. (2014). Individual risk stratification of gastric cancer: Evolving concepts and their impact on clinical practice. Best Practice and Research in Clinical Gastroenterology, 28(6), 1043–1053. doi:10.1016/j.bpg.2014.09.002