Specific serology for emerging human coronaviruses by protein microarray

Reusken, Chantal; Mou, Huihui; Godeke, Gert-Jan; van der Hoek, Lia; Meyer, Bernhard; Müller, Marcel; Haagmans, Bart; de Sousa, Rita; Schuurman, N.; Dittmer, U.; Rottier, Peter; Osterhaus, Albert; Drosten, Christian; Bosch, Berend Jan; Koopmans D.V.M., Marion

We present a serological assay for the specific detection of IgM and IgG antibodies against the emerging human coronavirus hCoV-EMC and the SARS-CoV based on protein microarray technology. The assay uses the S1 receptor-binding subunit of the spike protein of hCoV-EMC and SARS-CoV as antigens. The assay has been validated extensively using putative cross-reacting sera of patient cohorts exposed to the four common hCoVs and sera from convalescent patients infected with hCoV-EMC or SARS-CoV.

Additional Metadata
Persistent URL	hdl.handle.net/1765/87235
Journal	Eurosurveillance
Grant	This work was funded by the European Commission 7th Framework Programme; grant id fp7/223498 - European management platform for emerging and re-emerging infectious disease entities (EMPERIE)
Organisation	Department of Virology
Citation APA Style AAA Style APA Style Cell Style Chicago Style Harvard Style IEEE Style MLA Style Nature Style Vancouver Style American-Institute-of-Physics Style Council-of-Science-Editors Style BibTex Format Endnote Format RIS Format CSL Format DOIs only Format	Reusken, C., Mou, H., Godeke, G.-J., van der Hoek, L., Meyer, B., Müller, M., … Koopmans, M., D.V.M. (2013). Specific serology for emerging human coronaviruses by protein microarray. Eurosurveillance, 18(14), 2–7. Retrieved from http://hdl.handle.net/1765/87235

View at Pubmed

Free Full Text ( Final Version , 294kb )

Specific serology for emerging human coronaviruses by protein microarray

Publication

Publication

About

Specific serology for emerging human coronaviruses by protein microarray

Publication

Publication

Workflow

Workflow

Add Content