Background Knowledge of the HIV status in patients with tuberculosis (TB) and vice versa is crucial for proper individual patient management, while knowledge of the prevalence of co-infection guides preventive and therapeutic strategies. The aim of the study was to assess if national disease databases on TB and HIV are adequate sources to provide this information. Methods A two way capture-recapture analysis to assess the completeness of the registers, and to obtain the prevalence of TB-HIV co-infection in the Netherlands in the years 2002-2012. Results HIV testing was performed in less than 50% of the patients with TB. Of the 932 TB-HIV infected patients, just 293 (31.4%) were registered in both registers. Under-reporting of TB-HIV co-infection ranged from 50% to 70% in the national TB register, and from 31% to 37% in the HIV database. Prevalence of TB-HIV co-infection in the Netherlands in 2012 was 7.1% (95% CI 6.0% to 8.3%), which was more than double of the prevalence estimated from the national TB database. Conclusions TB-HIV co-infection is markedly underreported in national disease databases. There is an urgent need for improved registration and preferably a routine data exchange between the two surveillance systems.

dx.doi.org/10.1136/jech-2015-206680, hdl.handle.net/1765/87710
Journal of Epidemiology and Community Health
Department of Internal Medicine

van Leth, F, Evenblij, K, Wit, F.W.N.M, Kiers, A, Sprenger, H, Verhagen, M, … Verbon, A. (2016). TB-HIV co-infection in the Netherlands: Estimating prevalence and under-reporting in national registration databases using a capture-recapture analysis. Journal of Epidemiology and Community Health, 70(6), 556–560. doi:10.1136/jech-2015-206680