The Magazine Wharf area, Freetown, Sierra Leone was a focus of ongoing Ebola virus transmission from late June 2015. Viral genomes linked to this area contain a series of 13 T to C substitutions in a 150 base pair intergenic region downstream of viral protein 40 open reading frame, similar to the Ebolavirus/H.sapienswt/ SLE/2014/Makona-J0169 strain (J0169) detected in the same town in November 2014. This suggests that recently circulating viruses from Freetown descend from a J0169-like virus.

doi.org/10.2807/1560-7917.ES.2015.20.40.30035, hdl.handle.net/1765/87781
Eurosurveillance
Department of Virology

Smits, S.L, Pas, S.D, Reusken, C.B.E.M, Haagmans, B.L, Pertile, P, Cancedda, C, … Koopmans, M.P.G, D.V.M. (2015). Genotypic anomaly in ebola virus strains circulating in magazine wharf Area, Freetown, Sierra Leone, 2015. Eurosurveillance, 20(40). doi:10.2807/1560-7917.ES.2015.20.40.30035