Hypertensive cardiomyopathy is a common complication of hypertension, with a prevalence ranging from 12% to 26%. It is associated with an increased cardiac mortality and morbidity. Lifestyle changes and antihypertensive therapy usually have a significant, but relatively small effect on left ventricular hypertrophy (LVH), which is associated with a reduction in cardiovascular risk. In this paper, we describe a 39-year-old woman with severe LVH. On transthoracic echocardiogram there was concentric LVH, systolic function was a mildly reduced and there was diastolic dysfunction grade III. After only 6 months of therapy with a combination of antihypertensive agents, the left ventricular mass index was reduced by 29%, systolic function was normal and the diastolic dysfunction improved to grade I. This paper shows that in hypertensive cardiomyopathy, even severe LVH can be completely reversible.

doi.org/10.1136/bcr-2015-212908, hdl.handle.net/1765/87973
BMJ Case Reports
Department of Cardiology

Holl, M. J., van de Poll, S., & Michels, M. (2016). Complete reversal of hypertensive cardiomyopathy after initiating combined antihypertensive therapy. BMJ Case Reports, 2016. doi:10.1136/bcr-2015-212908