Different planning and treatment systems for intracranial stereotactic radiosurgery available in the Netherlands are compared. The systems for intracranial radiosurgery include: Gamma Knife, Cyberknife, Novalis, and Tomotherapy. Electronic data of 5 patients was transferred to all participating centres and treatment plans were generated according to 2 different prescription protocols. For this study, plans were also generated for a conventional linac. Even systems with a high resolution (Gammaknife and Novalis) have conformity indices in violation with RTOG guidelines (CI > 2.5) when target volumes of <0.5 cc are treated. For medium sized targets (0.5-1 cc) all systems performed reasonably well, but for the different systems a large range of conformity indices was seen (1.1 to 3.7). The differences are partly system dependent but depend also on specific planning choices made. For larger target volumes (>1 cc), all systems perform well. The workload of the different techniques was comparable although the treatment times were usually longer for Gamma Knife radiosurgery. We conclude that small targets should be treated by dedicated systems, larger volumes (>0.5-1 cc) can also be treated using conventional treatment systems equipped with a MLC.

IGRT, Intracranial stereotactic radiotherapy, Radiosurgery, Treatment plan evaluation
hdl.handle.net/1765/88045
Technology in Cancer Research and Treatment
Erasmus MC: University Medical Center Rotterdam

Schoonbeek, A, Monshouwer, R, Hanssens, P, Raaijmakers, E, Nowak, P.J.C.M, Marijnissen, J.P, … van der Maazen, R.W. (2010). Intracranial radiosurgery in the Netherlands. A planning comparison of available systems with regard to physical aspects and workload. Technology in Cancer Research and Treatment, 9(3), 279–289. Retrieved from http://hdl.handle.net/1765/88045