Aims: Renal denervation is a potential new treatment therapy for resistant hypertension. However, anatomic vascular variations might complicate the procedure and increase complications. A radial approach offers easier renal artery access and is associated with a decreased risk of vascular access complications. Methods and results: We describe the first-in-man use of a radial access ultrasound-based renal denervation device (Radiance™; ReCor, Palo Alto, CA, USA) in two patients with therapy-resistant hypertension. Both procedures were uneventful and resulted in significant blood pressure reductions at three-month follow-up (mean office blood pressure drop [-40/-29 mmHg]; mean ambulatory blood pressure drop [-11/-8 mmHg]). Conclusions: Radial access renal artery denervation using the Radiance catheter appears to be safe and effective and should be considered an alternative option in patients referred for renal denervation.

First-in-man, Radial, Renal denervation, Ultrasound,
Department of Cardiology

Daemen, J, & van Mieghem, N.M. (2015). First-in-man radial access renal denervation with the ReCor Radiance™ catheter. EuroIntervention, 10(10), 1209–1212. doi:10.4244/EIJY14M12-03