Hypereosinophilic syndrome (HES) is a diverse group of rare disorders, defined by persistent peripheral blood eosinophilia (>1500 per mm3), the absence of a primary cause of eosinophilia (such as parasitic or allergic disease), and evidence of eosinophil-mediated end-organ damage. Arterial aneurysms have been previously reported in these patients. This is the first report of a patient with HES and multiple venous aneurysms, causing recurrent pulmonary thromboembolism. Venous aneurysms can represent eosinophil-mediated, potentially fatal end-organ damage in patients with HES.

chronic venous insufficiency, Hypereosinophilic syndrome, venous aneurysms
dx.doi.org/10.1177/0268355514564176, hdl.handle.net/1765/88743
Phlebology
Department of Dermatology

Malskat, W.S.J, Racz, E, ten Raa, S, Lugtenburg, P.J, Hegt, V.N, & de Maeseneer, M.G.R. (2016). Multiple venous aneurysms in a patient with hypereosinophilic syndrome. Phlebology, 31(1), 66–68. doi:10.1177/0268355514564176