BACKGROUND: In psychotic disorders it is the stage of development of the disease which mainly determines the prognosis and the effectiveness of treatment. AIM: To describe and to refine the current staging and profiling of psychotic disorders and to propose a way in which to describe the course of dimensions of psychoses. METHOD: We searched the literature for articles relating to the staging of psychotic disorders. RESULTS: McGorry e.a. developed a simple classification into stages which is currently applicable to research and clinical practice. We propose a further refinement in the form of a graph from which one can see in a glance the history of clinically relevant variation. CONCLUSION: Research into the prodromal stages of diseases is needed in order to elucidate the pathophysiological mechanisms that the stages have in common and to reveal the pathways of differential development.

Early detection, Profiling, Psychotic disorders, Staging
Tijdschrift voor Psychiatrie
Erasmus MC: University Medical Center Rotterdam

de Haan, L, Klaassen, R.M.C, Van Beveren, L, Wunderink, L, Rutten, B.P.F, & van Os, J. (2012). Psychotic disorders: The need for staging. Tijdschrift voor Psychiatrie, 54(11), 927–933. Retrieved from