Current approach to intravascular volume optimization is made from a macrohemodynamic perspective. However, several situations wherein macrocirculatory and microcirculatory coherence is lost have been described. Future clinical trials should explore the usefulness of integrating the microcirculatory evaluation in fluid optimization.

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Current Opinion in Critical Care
Department of Intensive Care

Gruartmoner, G., Mesquida, J., & Ince, C. (2015). Fluid therapy and the hypovolemic microcirculation. Current Opinion in Critical Care (Vol. 21, pp. 276–284). doi:10.1097/MCC.0000000000000220