Current approach to intravascular volume optimization is made from a macrohemodynamic perspective. However, several situations wherein macrocirculatory and microcirculatory coherence is lost have been described. Future clinical trials should explore the usefulness of integrating the microcirculatory evaluation in fluid optimization.

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doi.org/10.1097/MCC.0000000000000220, hdl.handle.net/1765/88837
Current Opinion in Critical Care
Department of Intensive Care