Identification of microRNAs in human plasma
In recent years, microRNAs (miRNA) have been demonstrated to be present in body fluids and may therefore serve as diagnostic markers for diseases. By characterizing miRNA profiles in plasma, a miRNA signature may potentially be developed as a diagnostic and risk assessment tool for particular (patho)physiological states. This chapter describes the isolation, purification, identification, and sequencing of human plasma miRNAs.
|Human, miRNA, Plasma, RNA isolation, Whole-genome sequencing|
|Organisation||Department of Internal Medicine|
van der Eerden, B.C.J, Alves, R.D.A.M, Kockx, C, Ozgur, Z, Schreuders-Koedam, M, van de Peppel, J, … van Leeuwen, J.P.T.M. (2014). Identification of microRNAs in human plasma. doi:10.1007/978-1-4939-1619-1_7