2015
Polygenic risk scores for schizophrenia and bipolar disorder predict creativity
Publication
Publication
Nature Neuroscience , Volume 18 - Issue 7 p. 953- 955
We tested whether polygenic risk scores for schizophrenia and bipolar disorder would predict creativity. Higher scores were associated with artistic society membership or creative profession in both Icelandic (P = 5.2 × 10 â '6 and 3.8 × 10 â '6 for schizophrenia and bipolar disorder scores, respectively) and replication cohorts (P = 0.0021 and 0.00086). This could not be accounted for by increased relatedness between creative individuals and those with psychoses, indicating that creativity and psychosis share genetic roots.
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| doi.org/10.1038/nn.4040, hdl.handle.net/1765/91119 | |
| ERIM Top-Core Articles | |
| Nature Neuroscience | |
| Organisation | Department of Epidemiology |
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Power, R. A., Steinberg, S., Bjornsdottir, G., Rietveld, N., Abdellaoui, A., Nivard, M. M., Johannesson, M., Galesloot, T., Hottenga, J. J., Willemsen, G., Cesarini, D., Benjamin, D. J., Magnusson, P. K. E., Ullén, F., Tiemeier, H., Hofman, A., van Rooij, F., Walters, B., Sigurdsson, E., … Zwart, J.-A. (2015). Polygenic risk scores for schizophrenia and bipolar disorder predict creativity. Nature Neuroscience, 18(7), 953–955.https://doi.org/10.1038/nn.4040 |
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