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P.P.A. Lestrade (Pieter), J.F. Meis (Jacques F.), J.P.A. Arends (Jan), M.T. van der Beek (Martha), E.I.G.B. de Brauwer (E. I G B), K. van Dijk (Karin), S.C. de Greeff (Sabine C.), P.-J. Haas (Pieter-Jan), C.J. Hodiamont (Caspar J.), E. Kuijper, et al. T. Leenstra (Tjalling), A.E. Muller (Anouk), A. Oude Lashof (A.), B.J.A. Rijnders (Bart), E. Roelofsen (Eveline), W. Rozemeijer (Wouter), M. Tersmette (Mathijs), E.M. Terveer (Elizabeth M.), C.M. Verduin (Cees M.), M.J.H.M. Wolfhagen, W.J. Melchers (Willem) and P.E. Verweij (Paul)

2016

Diagnosis and management of aspergillosis in the Netherlands: A national survey

Publication

Publication

Mycoses , Volume 59 - Issue 2 p. 101- 107

A survey of diagnosis and treatment of invasive aspergillosis was conducted in eight University Medical Centers (UMCs) and eight non-academic teaching hospitals in the Netherlands. Against a background of emerging azole resistance in Aspergillus fumigatus routine resistance screening of clinical isolates was performed primarily in the UMCs. Azole resistance rates at the hospital level varied between 5% and 10%, although rates up to 30% were reported in high-risk wards. Voriconazole remained first choice for invasive aspergillosis in 13 out of 16 hospitals. In documented azole resistance 14 out of 16 centres treated patients with liposomal amphotericin B.

Additional Metadata
Keywords Aspergillosis, Azole resistance, Treatment
Persistent URL doi.org/10.1111/myc.12440, hdl.handle.net/1765/91210
Journal Mycoses
Organisation Department of Medical Microbiology and Infectious Diseases
Citation
Lestrade, P.P.A, Meis, J.F, Arends, J.P.A, van der Beek, M.T, de Brauwer, E.I.G.B, van Dijk, K, … Verweij, P.E. (2016). Diagnosis and management of aspergillosis in the Netherlands: A national survey. Mycoses, 59(2), 101–107. doi:10.1111/myc.12440


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