Management of encapsulating peritoneal sclerosis: A guideline on optimal and uniform treatment
The Netherlands Journal of Medicine , Volume 69 - Issue 11 p. 500- 507
Encapsulating peritoneal sclerosis (EPS) represents a rare complication of long-term peritoneal dialysis (PD). It is characterised by diffuse peritoneal membrane fibrosis, progressive intestinal encapsulation and the clinical spectrum of intestinal obstruction. The pathogenesis is as yet not well understood but includes inflammation, angiogenesis and fibrosis. The current diagnosis of EPS lacks specificity and relies on clinical, radiographic or macroscopic evaluation. There is no general agreement on managing EPS although accumulating clinical data suggest drug treatment (steroids, tamoxifen), surgery (enterolysis) or a combination of both. Here, we provide a short overview on the current knowledge of EPS, with a focus on treatment. Moreover, we present a diagnostic and a therapeutic algorithm for EPS based on the best available published data and our combined experience.
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|The Netherlands Journal of Medicine|
|Organisation||Department of Internal Medicine|
Habib, S.M, Betjes, M.G.H, Fieren, M.W.J.A, Boeschoten, E.W, Abrahams, A.C, Boer, W.H, … Korte, M.R. (2011). Management of encapsulating peritoneal sclerosis: A guideline on optimal and uniform treatment. The Netherlands Journal of Medicine (Vol. 69, pp. 500–507). Retrieved from http://hdl.handle.net/1765/91250