Tumor volume was measured in 344 totally embedded radical prostatectomy specimens of screen detected prostate cancer cases. In univariate analyses, tumor volume was predictive for biochemical and local progression, metastasis and mortality. In multivariable analyses, tumor volume did not add prognostic value to routinely assessed pathological parameters, like tumor stage, Gleason score, seminal vesicle invasion and surgical margin status. Therefore, there seems to be little reason to routinely measure tumor volume in RP specimens.

Prostate cancer, Radical prostatectomy, Tumorvolume
hdl.handle.net/1765/91267
Nederlands Tijdschrift voor Urologie
Erasmus MC: University Medical Center Rotterdam

Wolters, T, Roobol-Bouts, M.J, van Leeuwen, P.J, van den Bergh, R.C.N, Hoedemaeker, R.F, Leenders, G.J.H.L, … van der Kwast, Th.H. (2010). Should prostate tumor volume routinely be reported by the pathologist?: The prognostic value of tumor volume in prostate cancer. Nederlands Tijdschrift voor Urologie, 18(4), 110–117. Retrieved from http://hdl.handle.net/1765/91267