Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used for pain relief and antiinflammatory purposes. They are often combined with proton pump inhibitors (PPIs), the most potent blockers of gastric acid secretion to reduce gastroduodenal complications of NSAID use. This thesis studied the use and safety of NSAIDs and PPIs.

M.C.J.M. Sturkenboom (Miriam) , E.J. Kuipers (Ernst) , P.M. Coloma (Preciosa)
Erasmus University Rotterdam
Financial support for the publication of this thesis was generously provided by: Erasmus MC, Interdisciplinary Processing of Clinical Information (IPCI) group, Nederlands Bijwerkingen Fonds, Nederlandse Hartstichting, Nederlandse Vereniging voor Gastroenterologie, Chipsoft B.V., Dr. Falk Phama Benelux B.V., Ferring B.V.

The work described in this thesis was conducted at the department of Medical Informatics (within the IPCI; Interdisciplinary Processing of Clinical Information project) and Gastroenterology and Hepatology at the Erasmus University Medical Center, Rotterdam, the Netherlands. Parts of this thesis were conducted within international collaborative projects funded by the European Commission in the 7th Framework Programme; EU-ADR (Exploring and Understanding Adverse Drug Reactions; under grant agreement number 215847–The EU-ADR Project), SOS (Safety Of non-Steroidal Anti-inflammatory drugs; under grant agreement number 223495 - the SOS project) and SAFEGUARD (Safety Evaluation of Adverse Reactions in Diabetes; under grant agreement number 282521 - the SAFEGUARD project), and a project funded by AstraZeneca PLC.

Erasmus MC: University Medical Center Rotterdam

Masclee, G.M.C. (2016, June 29). Effects of Non-Steroidal Anti-Inflammatory Drugs on the Gastrointestinal and Cardiovascular System. Erasmus University Rotterdam. Retrieved from