Radiolabeled gastrins in CCK2R-positive tumor targeting
Toward improved diagnostic efficacy via in situ enzyme-inhibition approaches
Radioactieve gasrtines voor CCK2R-positieve tumoren - naar verbeterde diagnostiek door in situ enzymremming
In this thesis, several novel radiolabeled gastrin analogs were developed preclinically in vitro as well as in vivo in animal models.
In addition, the effect of in situ enzyme inhibition on metabolic stability and tumor uptake of the same gastrin radioligands was investigated.
|Promotor||M. de Jong (Marion) , T. Maina (Theodosia) , B.A. Nock (Berthold)|
|Publisher||Erasmus University Rotterdam|
Kaloudi, A. (2016, July 5). Radiolabeled gastrins in CCK2R-positive tumor targeting. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/93109