In this thesis, I attempt to provide additional evidence regarding the role of traditional and novel anthropometric measures in prediction of cardiovascular disease (CVD) and mortality.
Furthermore, I evaluate the metabolic health among older adults in association with CVD and additionally explore how duration of overweight could impact the metabolic risk. I also focus on the impact of obesity on life expectancy with and without CVD, and explore the trajectories of obesity development before the diagnosis of CVD.
Finally, I evaluate the impact of physical activity in the association between overweight, obesity and CVD and further explore the types of physical activity in association with coronary heart disease, CVD and life expectancy.

O.H. Franco (Oscar) , M. Kavousi (Maryam)
Nederlandse Hartstichting (Netherlands Heart Foundation)

All studies described in this thesis were performed within the Rotterdam Study, which is supported by Erasmus Medical Center and Erasmus University Rotterdam, the Netherlands Organization for Scientific Research (NWO), the Netherlands Organization for Health Research and Development (ZonMw), the Dutch Heart Foundation, the Research Institute for Diseases in the Elderly (RIDE), the Ministry of Education, Culture and Science, the Ministry of Health, welfare and Sports, the European Commission (DG XII), and the municipality of Rotterdam.

The research described in this thesis is supported by Erasmus Mundus Western Balkans (ERAWEB), a project funded by the European Commission.

Department of Epidemiology

Dhana, K. (2016, July 5). Obesity, Physical Activity, and Cardio-metabolic Disorders in Older Adults. Retrieved from