Craniosynostosis is a rare congenital disorder, characterized by the premature fusion of skull suture(s) resulting in an abnormal skull shape. These children are at risk for obstructive sleep apnea, but also for cranio-cerebral disproportion, hydrocephalus, venous hypertension and abnormal cerebral blood flow. All these factors contribute to the development of intracranial hypertension, i.e., raised intracranial pressure.

Additional Metadata
Keywords Craniosynostosis
Promotor I.M.J. Mathijssen (Irene) , K.F.M. Joosten (Koen)
Publisher Erasmus University Rotterdam
ISBN 978-94-6233-332-1
Persistent URL
Spruijt, B. (2016, September 30). Craniosynostosis: Obstructive sleep apnea in a unifying theory for intracranial hypertension.. Erasmus University Rotterdam. Retrieved from