We developed attenuation imaging in OCT for atherosclerotic tissue characterization and validated the method ex and in-vivo. We introduced an en-face map of attenuation in the whole artery for plaque visualization. We quantified the attenuation derived from OCT and derived an index for the plaques.
A single centre clinical study (OC3T study) was conducted to validate the index to identify thin cap fibroatheromas. We also demonstrated the utility of the attenuation maps and the index in clinical studies as corresponding well with a visual assessment of LCP in the OCT data by expert readers .

, ,
A.F.W. van der Steen (Ton) , G. van Soest (Gijs)
Erasmus University Rotterdam
The research described in theis thesis was supported by a grant of the Dutch Heart Foundation (No. 2010B064) Financial support by the Dutch Heart Foundation for the publication of theis thesis is gratefully acknowledged.
Department of Cardiology

Gnanadesigan, M. (2016, June 17). Intravascular OCT tissue type imaging by automated optical attenuation analysis. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/93215