This paper describes the kinetics of fibroblastic colony forming units (CFU‐f) in murine blood after phenylhydrazine‐induced haemolytic anaemia and their subsequent migration into haemopoietic organs. Murine blood contained 5.3 φ 0.8 CFU‐f per 106 nucleated cells. Absence of particle ingestion and factor VIII‐related antigen in addition to the enzyme pattern in CFU‐f‐derived cells confirmed that these cells did not have a macrophage‐like or endothelial nature. Phenylhydrazine treatment of mice resulted in a 3‐fold increase in blood CFU‐f numbers which was accompanied by increases in blood cellularity and granulocyte‐macrophage progenitor numbers. When both partners of CBA/N and CBA/T6T6 mice in parabiosis had been treated with phenylhydrazine, spleens and femoral bone marrow of both mice were shown to contain partner‐derived CFU‐f. These data suggest that circulating CFU‐f represent a stromal cell population which can migrate into haemopoietic organs. Copyright,
Cell Proliferation
Biophysical Genomics, Department Cell Biology & Genetics

Piersma, A. H., Ploemacher, R., Brockbank, K. G. M., Nikkels, P. G. J., & Ottenheim, C. P. E. (1985). Migration of Fibroblastoid Stromal Cells In Murine Blood. Cell Proliferation, 18(6), 589–595. doi:10.1111/j.1365-2184.1985.tb00702.x