The cytoskeleton is of great importance for cell division, cell shape, cell migration and intracellular transport.
This thesis describes how one of the three main cytoskeletal networks, namely the microtubule (MT) network, is regulated by MT plus-end tracking proteins (+TIPs) named “Navigators”.
Furthermore, it describes the mechanisms by which two other +TIPs, named CLIP170 and EB1, associate with microtubule plus-ends.

Additional Metadata
Promotor F.G. Grosveld (Frank) , N.J. Galjart (Niels)
Publisher Erasmus University Rotterdam
Sponsor This research was supported by the Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO). Printing of this thesis was financially supported by the Erasmus MC and the J.E. Jurriaanse Stichting
ISBN 978-90-8570-291-7
Persistent URL
van Haren, J.A.J. (2009, June 10). Navigating Cells and Cytoskeletal Networks with a Novel Family of AAA-ATPases. Erasmus University Rotterdam. Retrieved from