In this dosimetric comparison study it was shown that IMPT with robust planning reduces dose to surrounding organs in cervical and endometrial cancer treatment compared with IMRT. Especially for the para-aortic region, clinically relevant dose reductions were obtained for kidneys, spinal cord and bowel, justifying the use of proton therapy for this indication.

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Radiotherapy & Oncology
Erasmus MC: University Medical Center Rotterdam

Sande, M.A.E. (Mariska) van de, Creutzberg, C., van de Water, S., Sharfo, A. W., & Hoogeman, M. (2016). Which cervical and endometrial cancer patients will benefit most from intensity-modulated proton therapy?. Radiotherapy & Oncology, 120(3), 397–403. doi:10.1016/j.radonc.2016.06.016