1988
Endothelialization of Intravascular Stents
Publication
Publication
Journal of Interventional Cardiology: an international forum for global cardiovascular therapies , Volume 1 - Issue 2 p. 109- 120
Wide clinical application of intravascular stenting devices is currently limited by occlusion or intraluminal narrowing caused by thrombosis and neointimal thickening in a considerable percentage of implantations. We studied the possibility of seeding one of the currently availiable stents, a stainless steel, self‐expandable wire‐mesh, with endothelial cells in vitro. Endothelial cells, derived from human umbilical cord veins, could be successfully attached to stent filaments. In vivo stent implantations in porcine femoral arteries showed complete covering of stent wires by endothelium after 1 week. We conclude that coating of stents with autologous endothelial cells prior to implantation might protect against early thrombosis during the period in which a neointima is formed. (J Interven Cardiol 1988:1:2) Copyright
| Additional Metadata | |
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| doi.org/10.1111/j.1540-8183.1988.tb00395.x, hdl.handle.net/1765/94078 | |
| Journal of Interventional Cardiology: an international forum for global cardiovascular therapies | |
| Organisation | Department of Cardiology |
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van der Giessen, W., Serruys, P., W.J. Visser, Verdouw, P., van Schalkwijk, P., & Jongkind, J. F. (1988). Endothelialization of Intravascular Stents. Journal of Interventional Cardiology: an international forum for global cardiovascular therapies, 1(2), 109–120. doi:10.1111/j.1540-8183.1988.tb00395.x |
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