The aim of the thesis is to evaluate overdiagnosis in breast cancer screening in well established national screening programs. To achieve this we addressed the following research questions:
The detection of ductal carcinoma in situ (DCIS) seems to be associated with a higher risk of overdiagnosis. What is the impact of the transition to digital mammography on the amount of DCIS diagnosed with screening?
Overdiagnosis is a well debated issue in breast cancer screening, but not in screening for cervical cancer screening. Is there overdiagnosis in cervical cancer screening, and how does this relate to the overdiagnosis rate in breast cancer screening?
What is the impact of DCIS on overdiagnosis estimates in breast cancer screening?
Is the Norwegian Breast Cancer Screening Program generating overdiagnosis, and at what level?
Is the Norwegian Breast Cancer Screening Program effective in reducing breast cancer mortality despite the occurrence of overdiagnosis?

H.J. de Koning (Harry) , E.A.M. Heijnsdijk (Eveline)
Erasmus University Rotterdam
The studies reported in this thesis were primarily funded by the National Institute for Public Health and the Environment, RIVM. For any grant pertaining to specific studies the reader is referred to the individual papers published in their respective journals.
Erasmus MC: University Medical Center Rotterdam

van Luijt, P. (2016, November 29). Overdiagnosis in the Dutch and Norwegian breast cancer screening program. Retrieved from