The aim of this thesis is to unravel the relation between shell properties and the acoustic response of single microbubbles. Next, the most stable and acoustically best performing UCAs are also investigated in vitro for therapeutic applications by means of sonoporation, and for in vivo diagnostic imaging applications.

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N. de Jong (Nico) , A.F.W. van der Steen (Ton) , K. Kooiman (Klazina)
Erasmus University Rotterdam
Financial support by the Dutch Heart Foundation and the Dutch Kidney Foundation for the publication of this thesis is gratefully acknowledged.
Department of Cardio-Thoracic Surgery

van Rooij, T. (2017, January 18). Ultrasound Contrast Agents for Imaging and Therapy. Retrieved from