Classifying the additional morbidities of Gaucher disease

When an additional morbidity occurs in a patient already known to have a primary condition, these diseases can be related in different ways:

1. the conditions are causally related, so called associated conditions
2. the second disease is a complication of the treatment of the index disease, or
3. they are unrelated, the second condition occurring by chance.

In Gaucher disease, additional morbidities are increasingly recognized, specifically in those patients that have been treated with enzyme replacement therapy.