Newly identified viruses in human gastroenteritis : Pathogens or not?

Infectious diarrheal diseases remain a common cause of morbidity and mortality especially in children younger than 5 years in low-income and middle-income countries.1 The most common viral pathogens known to cause acute gastroenteritis in humans are rotavirus A, norovirus, sapovirus, enteric adenoviruses and astrovirus. In addition to these well-established etiologies, a large number of moderate to severe diarrhea cases go without etiological diagnosis and many unanswered questions surrounding the burden and etiology of diarrhea, and the factors determining clinical expression of infection remain. [...]

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