Aims: Our aim was to test the feasibility and safety of the transfemoral PulseCath iVAC 2L (PulseCath, Amsterdam, The Netherlands). Methods and results: Circulatory support devices are helpful adjunctive tools to perform high-risk percutaneous coronary interventions (PCI). The PulseCath iVAC 2L is a novel pulsatile circulatory support system capable of generating output of up to 2 L/min. We performed a prospective clinical pilot study enrolling 14 patients who underwent high-risk PCI under protection with the iVAC 2L. Median age was 74 (56-84) years. Implantation of the iVAC 2L was successful in 13 (93%) patients. Median device flow was 1.4 (1.1-2.0) L/min. Total support time was 67 (23-149) minutes. The use of iVAC 2L support was associated with a better mean arterial pressure and cardiac output during the procedure. Angiographic success was 100%. There was one major procedural complication related to the 19 Fr access sheath. There were no major adverse events at three-month follow-up. Conclusions: Circulatory support with the iVAC 2L device is feasible and safe in patients undergoing high-risk PCI.

Additional Metadata
Keywords Haemodynamics, High-risk procedure, Intra-aortic balloon pump, Mechanical circulatory support, Percutaneous coronary intervention
Persistent URL dx.doi.org/10.4244/EIJ-D-16-00371, hdl.handle.net/1765/98772
Journal EuroIntervention
Citation
Uil, C.A.D. (Corstiaan A. Den), Daemen, J, Lenzen, M.J, Maugenest, A.M, Joziasse, L. (Linda), van Geuns, R.J.M, & van Mieghem, N.M. (2017). Pulsatile iVAC 2L circulatory support in high-risk percutaneous coronary intervention. EuroIntervention, 12(14), 1689–1696. doi:10.4244/EIJ-D-16-00371