Het optimaliseren van Mohs micrografische chirurgie door de revisie van mohscoupes

The success of Mohs surgery depends on correct interpretation of the slides. This retrospective study investigated how often pathologists detected incompletely excised basal cell carcinoma (BCC) during revision of Mohs slides in 1653 BCCs treated with Mohs surgery. Thereby, we determined risk factors for incompletely excised BCCs. Incompletely excised BCCs were detected in 31 cases (2%), in which defects < 20 mm in diameter were an independent risk factor (odds ratio 3.58, 95% confidence interval 1.55-8.28). Other studied variables (i.e. aggressive subtype, previously treated BCC, location on nose and < 2 Mohs stages) did not affect the risk of incompletely excised BCCs. This study showed that the additional review of Mohs slides increased accurate interpretation, especially in large BCCs. Therefore, the additional review of Mohs slides might prevent skin cancer recurrence.