In this issue of Molecular Cell, Xie et al. (2017) introduce Mosaic-seq, a powerful technology that combines CRISPRi and single-cell RNA-seq. This method enables the high-throughput assessment of contributions of enhancers to gene regulation.

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doi.org/10.1016/j.molcel.2017.03.018, hdl.handle.net/1765/99722
Molecular Cell
Erasmus MC: University Medical Center Rotterdam

van Arensbergen, J. (Joris), & van Steensel, B. (2017). Functional Enhancer Screening in Single Cells. Molecular Cell, 66(2), 167–168. doi:10.1016/j.molcel.2017.03.018