In this issue of Molecular Cell, Xie et al. (2017) introduce Mosaic-seq, a powerful technology that combines CRISPRi and single-cell RNA-seq. This method enables the high-throughput assessment of contributions of enhancers to gene regulation.

Additional Metadata
Keywords barcoding, CRISPRi, enhancer, functional screen, gene regulation, promoter, single-cell RNA sequencing
Persistent URL dx.doi.org/10.1016/j.molcel.2017.03.018, hdl.handle.net/1765/99722
Journal Molecular Cell
Citation
van Arensbergen, J. (Joris), & van Steensel, B. (2017). Functional Enhancer Screening in Single Cells. Molecular Cell, 66(2), 167–168. doi:10.1016/j.molcel.2017.03.018