There are many different cutaneous malignancies, but malignant melanoma, squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) represent approximately 98% of all skin cancers.In literature, these three skin cancers are often divided into melanoma and nonmelanoma skin cancers (NMSC; including BCC and SCC). However NMSC can be considered a misnomer, as there are many other rare cutaneous malignancies that are not a melanoma. A more appropriate term to classify BCC and SCC together could be keratinocyte carcinoma (KC) as they both arise from keratinocytes. Melanoma is the least common (about 11% of all skin cancers) but one of the most deadly types of skin cancer and develops from melanocytes. BCC is the most common skin cancer (approximately 70% of all skin cancers) and also the least dangerous of the three. However, substantial morbidity and cosmetic disfigurement can occur (figure 1), because around 80% of the BCCs are located within the chronically to the sun-exposed head and neck region. The studies presented in this thesis primarily focus on BCC.

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Financial support for the printing of this thesis was generously provided by Galderma, J.E. Jurriaanse Stichting, Abbott, Astellas, Pfi zer BV, Leo Pharma BV, Bauerfeind Benelux BV, Louis Widmer, Janssen-Cilag, Fagron, Eucerin, Integraal Kankercentrum Zuid and ZonMw.
H.A.M. Neumann (Martino) , T.E.C. Nijsten (Tamar)
Erasmus University Rotterdam
hdl.handle.net/1765/38167
Erasmus MC: University Medical Center Rotterdam

Flohil, S. (2012, December 20). Basal Cell Carcinoma in The Netherlands. Retrieved from http://hdl.handle.net/1765/38167