There is a pressing necessity for improving the knowledge about the etiology and clinical applicability of dietary restriction to optimize the effects of dietary restriction on surgical and disease-related stress resistance and postoperative outcome.
The aims of this thesis were to assess the effects of current and novel short-term dietary regimens in different models, to gain more insight into the mechanisms and to search for a clinically applicable dietary intervention in the surgical setting.

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Keywords Dietary restriction, fasting, live kidney donation, kidney transplantation, stress resistance, ischemia-reperfusion injury, microarray analysis, chemotherapy
Promotor J.N.M. IJzermans (Jan) , H. van Steeg (Harry) , R.W.F. de Bruin (Ron) , M.E.T. Dollé (Martijn)
Publisher Erasmus University Rotterdam
Sponsor This research was funded by the Strategic Research Program from the National Institute for Public Health and the Environment and the Ministry of Health, Welfare and Sport of the Netherlands (Protocol number: S/340005).
ISBN 978-94-6299-790-5
Persistent URL
Jongbloed, F. (2017, December 13). Dietary restriction as treatment modality : inducing resistance to ischemic and chemotherapy related stress. Erasmus University Rotterdam. Retrieved from