There is a pressing necessity for improving the knowledge about the etiology and clinical applicability of dietary restriction to optimize the effects of dietary restriction on surgical and disease-related stress resistance and postoperative outcome.
The aims of this thesis were to assess the effects of current and novel short-term dietary regimens in different models, to gain more insight into the mechanisms and to search for a clinically applicable dietary intervention in the surgical setting.

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This research was funded by the Strategic Research Program from the National Institute for Public Health and the Environment and the Ministry of Health, Welfare and Sport of the Netherlands (Protocol number: S/340005).
J.N.M. IJzermans (Jan) , H. van Steeg (Harry) , R.W.F. de Bruin (Ron) , M.E.T. Dollé (Martijn)
Erasmus University Rotterdam
Postgraduate School Molecular Medicine (MM)

Jongbloed, F. (2017, December 13). Dietary restriction as treatment modality : inducing resistance to ischemic and chemotherapy related stress. Retrieved from