Industry, regulators, health technology assessment (HTA) bodies, and payers are exploring the use of patient preferences in their decision-making processes. In general, experience in conducting and assessing patient preference studies is limited. Here, we performed a systematic literature search and review to identify factors and situations influencing the value of patient preference studies, as well as applications throughout the medical product lifecyle. Factors and situations identified in 113 publications related to the organization, design, and conduct of studies, and to communication and use of results. Although current use of patient preferences is limited, we identified possible applications in discovery, clinical development, marketing authorization, HTA, and postmarketing phases.

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Journal Drug Discovery Today
van Overbeeke, E, Whichello, C.L., Janssens, R, Veldwijk, J., Cleemput, I, Simoens, S, … Huys, I. (2019). Factors and situations influencing the value of patient preference studies along the medical product lifecycle: a literature review. Drug Discovery Today, 24(1), 57–68. Retrieved from