2019-06-01
Biomarkers for Infection in Children: Current Clinical Practice and Future Perspectives
Publication
Publication
The Pediatric Infectious Disease Journal , Volume 38 - Issue 6S Suppl 1 p. S7- S13
Biomarkers have become an integral part of the clinical decision-making process of clinicians dealing with febrile children. C-reactive protein, procalcitonin and white blood cell count are probably the most studied ones. Crucial to using biomarkers is the understanding of how a test result will alter post-test probabilities and then impact on clinical decision making. Improved analytical and computational platforms have enabled the next generation of advanced biomarker discovery studies. Promising combinations of candidate biomarkers for a diverse spectrum of febrile illnesses, such as viral and bacterial infections, have been identified using proteomics, RNA gene expression and metabolomics.
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doi.org/10.1097/INF.0000000000002318, hdl.handle.net/1765/117682 | |
VSNU Open Access deal | |
The Pediatric Infectious Disease Journal | |
Organisation | Department of Pediatrics |
Stol, K., Nijman, R., Van Herk, W., & van Rossum, A. (2019). Biomarkers for Infection in Children: Current Clinical Practice and Future Perspectives. The Pediatric Infectious Disease Journal, 38(6S Suppl 1), S7–S13. doi:10.1097/INF.0000000000002318 |