Mass spectrometry-based techniques can be applied to investigate collagen with respect to identification, quantification, supramolecular organization, and various post-translational modifications. The continuous interest in collagen research has led to a shift from techniques to analyze the physical characteristics of collagen to methods to study collagen abundance and modifications. In this review, we illustrate the potential of mass spectrometry for in-depth analyses of collagen.

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doi.org/10.1002/mas.21600, hdl.handle.net/1765/119611
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Mass Spectrometry Reviews
Department of Neurology

van Huizen, N., IJzermans, J., Burgers, P., & Luider, T. (2019). Collagen analysis with mass spectrometry. Mass Spectrometry Reviews. doi:10.1002/mas.21600