The studies in this doctoral thesis focus on thyroid hormone transporters, specifically monocarboxylate transporter (MCT) 8. The studies cover the whole spectrum from molecular studies on MCT8 structure and function to a phase II clinical trial with the thyroid hormone analogue Triac in patients with MCT8 deficiency.

Additional Metadata
Keywords Thyroid, thyroid hormone, thyroid hormone transporter, Monocarboxylate transporter 8, MCT8, MCT8 deficiency, Allan-Herndon-Dudley syndrome, AHDS, Organic Anion Transporting polypeptide 1C1, OATP1C1, OATP1C1 deficiency, Triac, thyroid hormone analogues
Promotor R.P. Peeters (Robin) , W.E. Visser (Wil Edward)
Publisher Erasmus University Rotterdam
ISBN 978-94-6375-719-5
Persistent URL
Note For copyright reasons there is a partial embargo for this dissertation
Groeneweg, S. (2020, February 11). Thyroid hormone transporters: from molecules to patients. Erasmus University Rotterdam. Retrieved from