A multicellular organism is build up of widely different cell types such as blood cells, neural cells, muscle cells and skin cells. The origin of all these cells is a single cell; the fertilized egg. With very few exceptions, all cells contain the same set of genes. Then what makes them different from one another morphologically and functionally? Essentially it is not the genes that determine the fate of these cells, but it is the expression of these genes that makes one cell different from another, resulting in an eye or hand or foot. The main aim of this thesis is to identify the factor(s) that act upstream and downstream of Oct6 in Schwann cells and to identify Oct6 interacting molecules that contribute to Oct6 function in Schwann cells.

The studies described in this thesis were supported by grants from the Netherlands Organisation of Scientific Research (NWO): NWO VICI grant 918.66.616, BSIK program 03038, ‘Stem cells in health and disease’, ALW grant 805.17.281 and the European Community’s Seventh Framework Program (FP7/2007-2013) under agreement No. HEALTH-F2-2008-201535 Financial support by the J.E.Jurrianse Stichting and ErasmusMC for the publication of this thesis is gratefully acknowledged.
D.N. Meijer (Dies)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

Jagalur, N. (2011, May 18). Role of Oct6 in Peripheral Nerve Myelination. Retrieved from http://hdl.handle.net/1765/37846