2010-06-25
Coronary atherosclerosis and wall shear stress: Towards application of CT angiography
Publication
Publication
Coronaire aderverkalking en wandschuifspanning: De (on)mogelijkheden van CT angiografie
Abstract
Vulnerable plaques are characterized by the presence of a large lipid pool, which is separated from the lumen by a thin fibrous cap, often infiltrated by macro phages [Schaar-04]. Rupture of this fibrous cap is generally regarded as one of the main underlying causes of cardiovascular events [Fa!k-95]. Rupture occurs when the stresses in the cap of the plaque exceed the strength of the cap [Lee-93]. The composition of the plaque plays a crucial role in the rupture process: it determines how blood pressure is translated into stresses in the wall, and composition also determines the strength of the tissue [Loree-94, Holzapfel-05].
| Additional Metadata | |
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| , , , , , , | |
| A.F.W. van der Steen (Ton) , P.J. de Feyter (Pim) | |
| Erasmus University Rotterdam | |
| Financial support by the Netherlands Heart Foundation and the School of Medical Physics and Engineering for the publication of this thesis is gratefully acknowledged. Additional financial support was kindly provided by lnfraReDx, Cardia lysis, Siemens Healthcare and Omines. | |
| hdl.handle.net/1765/77045 | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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van der Giessen, A. (2010, June 25). Coronary atherosclerosis and wall shear stress: Towards application of CT angiography. Retrieved from http://hdl.handle.net/1765/77045 |
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| Additional Files | |
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| 3130_Giessen-Alina-Gerarda-van-der.jpg Cover Image , 29kb | |
| Stellingen-van-der-Giessen.pdf , 21kb | |
