Regulation of Coding and Non-coding Genes: New insights obtained through analysis of high-throughput sequencing data

The genetic code of a cell is kept in its DNA. However, a vast number of functions of a cell are carried out by proteins. Through gene expression the genetic code can be expressed and give rise to proteins. The expression of genes into proteins follows two steps: transcription of DNA into RNA and translation of (messenger-)RNA into proteins. This thesis concerns these two steps in gene expression, which are very different from a molecular point-ofview.